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Donald Frei, MD

Dr. Donald Frei is an neuroInterventional surgeon based in Denver, Colorado


Medical School:  University of Cincinnati College of Medicine – Cincinnati, OH


Internal Medicine: Rush-Presbyterian-St. Luke’s Medical Center – Chicago, IL


Diagnostic Radiology: Tulane University Medical Center – New Orleans, LA


Neuroradiology/Endovascular Surgical Neuroradiology: Mallinckrodt Institute of Radiology,
Washington University – St. Louis, MO

Board Certifications

American Board of Radiology 1994
Certificate of Added Qualifications in Neuroradiology 1996

Areas of Interest

Endovascular Treatment of Acute Stroke

Endovascular Treatment of Aneurysms Intracranial

Extracranial Revascularization Techniques

Publications & Presentations

The FDA approval process for medical devices: an inherently flawed system or a valuable pathway for innovation? Accepted for publication, JNIS, 2012 May. Fargen KM, Frei D, et al.

Endovascular therapy of acute ischemic stroke: report of the Standards of Practice Committee of the Society of NeuroInterventional surgery. J Neurointerv Surg. 2012 Mar 1;4(2):87-93. Epub 2012 Jan. 24. Blackham KA, Frei D et al.

The Penumbra Stroke System: a technical review. J NeuroIntervent Surg 2011. doi:10.1136/neurintsurg-2011-010080, Yoo AJ, Frei D, Tateshima S, et al.

Styloidogenic Jugular Venous Compression Syndrome: Diagnosis and Treatment. Neurosurgery. 2011 Aug 19. [Epub ahead of print Dashti SR, Nakaji P, Hu YC, Frei DF, Abla AA, Yao T, Fiorella D

The POST trial: initial post-market experience of the Penumbra system: revascularization of large vessel occlusion in acute ischemic stroke in U.S. and Europe J NeuroIntervent Surg 2010. 2:341e344. doi:10.1136/jnis.2010.002600, Tarr R, Frei D, et al.

Multimodal imaging does not delay intravenous thrombolytic therapy in acute stroke. AJNR Am J Neuroradiol. 2011 May;32(5):864-8. Epub 2011 Feb 10. Salottolo KM, Fanale CV, Leonard KA, Frei DF, Bar-Or D.

Predictors of Good Clinical Outcomes, Mortality, and Successful Revascularization in Patients With Acute Ischemic Stroke Undergoing Thrombectomy Pooled Analysis…, Stroke. 2009. 40:3777-3783, Nogeira R, Frei D, et al.

The Penumbra Pivotal Stroke Trial Safety and Effectiveness of a New Generation of Mechanical Devices for Clot Removal in Intracranial Large Vessel Occlusive Disease Stroke. 2009. 40:2761-2768, Tarr R, Frei D, et al.

Comparison of Mechanical Embolectomy and Intraarterial Thrombolysis in Acute Ischemic Stroke within the MCA: MERCI and Multi MERCI compared to PROACT II, Neurocrit Care 2009. 10:43–49, Josephson S, Frei D, et al.

Demonstration and Partial Characterization of Parasite-Specific Immunoglobulin A Responses in Human Strongyloidiasis. Journal of Clinical Microbiology. 25: 1505-1510, 1987. Robert M Genta MD, Donald F Frei MD, Michael Linke